9.10% imidacloprid 

0.46% pyriproxyfen 

Imidacloprid attacks the flea's nervous system — paralyzing and ultimately killing it. Pyriproxyfen is an insect growth regulator (IGR) that mimics the juvenile growth hormone of fleas; this prevents immature flea stages from molting into the next stage of the life cycle and keeps them from developing into adult fleas. It also offers additional larvicidal properties when compared with imidacloprid alone. 

Advantage® II for Cats can be applied monthly, year-round to keep your patients protected from fleas. A single application of Advantage® II for Cats stops biting fleas for one month. 

However, if the cat has a severe infestation, re-treatment within a month may be necessary. Do not re-treat more often than once every 14 days for kittens or once every 7 days for small and large cats; after flea control is attained, your client can return to a monthly re-treatment schedule. 

Advantage® II for Cats is available in three weight bands: 

Advantage® II Kitten, 2-5lbs 

1 Sleeve of 6 2-Packs (o.23 mL tubes) 

Advantage® II Small cat, 5-9 lbs. 

1 Sleeve of 6 4-Packs (0.4 mL tubes) 

1 Sleeve of 6 6-Packs (0.4 mL tubes) 

Advantage® II Large cat, over 9 lbs. 

1 Sleeve of 6 4-Packs (0.8 mL tubes) 

1 Sleeve of 6 6-Packs (0.8 mL tubes) 

With an IGR (insect growth regulator) as part of your practice’s flea control plan, the flea life cycle is disrupted at multiple stages through different active ingredients and modes of action. This is often referred to as integrated flea control (IFC). The addition of an IGR to Advantage® II provides ovicidal properties, as well as additional larvicidal properties, to target flea infestations and kill flea life stages.